Patient related

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The course deals with the role of mitochondria in cancer development and progression. Bioenergetics of cancer, mitochondrial genetics and mitochondria-related signalling pathways are discussed in detail, as well as mitochondria-related aspects of cancer research such as aging, bioinformatics and mit ...
This is the closuring lecture of the course in Mitochondrial Metabolism and Cancer on how bioenergetics has helped progress in cell biology and human pathology, milestone discoveries regarding mitochondrial research are presented.
Cancer is a heterogeneous and complex genetic disease that drives the progressive transformation of normal cells into malignancy by a multistep ordered process. However, and in addition to the contribution of genetic mutations in the well established cancer genes (oncogenes and tumour suppressors), ...
In this course, we discuss the concept of variable metabolic remodeling and signaling in tumors, specifically the modifications in the main biochemical energy pathways observed in cultured cancer cells and excised tumors, as well as the concentration changes in various (onco)metabolites that partici ...
Complex cellular functions are often determined by the dynamic interactions occurring in networks of hundreds or thousands gene products that generate system-level properties largely unpredictable considering only the behaviour of individual nodes of the network. The phenotype of “in vitro” grow ...
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