Genetics + genomics > Clinical/medical genetics > Disease related (typology of disorder) > Cancer genetics > Growth regulation > Oncogenes
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The course deals with the role of mitochondria in cancer development and progression. Bioenergetics of cancer, mitochondrial genetics and mitochondria-related signalling pathways are discussed in detail, as well as mitochondria-related aspects of cancer research such as aging, bioinformatics and mit ...
Complex cellular functions are often determined by the dynamic interactions occurring in networks of hundreds or thousands gene products that generate system-level properties largely unpredictable considering only the behaviour of individual nodes of the network. The phenotype of “in vitro” grow ...
Gluscose is required for growing cells and therefore the increased vascular density of proliferating tissues serves their high glucose demand. This lecture will describe the particular metabolic pathways activated in growth and in tumors cells, that aim at directing nutrient s for biosynthesis, for ...
Cancer is always a genetic disease, as it results from genetic defects in cells. In the majority of cases, the accumulation of genetic changes in a tissue is random, and the tumour is termed sporadic. In a fraction of cases, however, all the cells of the body carry an inborn genetic defect, which in ...
Zvýšené riziko malignit u heterozygotů v rodinách pacientů s Nijmegen breakage syndromem Autoři: Seemanová E., 1Jarolím P., 2Seeman P., 3Varon R., 3Sperling K. Autoři - působiště: Oddělení klinické genetiky, Ústav biologie a lékařské genetiky 2. LF UK, Praha 1Ústav hematolog ...