Genetic linkage/linkage maps, recombination

Genetics + genomics > Statistical genetics > Mathematical models used in statistical genetics > Formal genetics > Genetic linkage/linkage maps, recombination
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A series of Lectures on Medical and molecular genetics, given during the 19th Course in Medical Genetics, 26th April - 2nd May, 2006, Bertinoro, Italy. GENETIC ANALYSIS: H.Brunner: Genotypes and phenotypes; G.Stevanin: Linkage analysis; G.Romeo: From mendelian genetics to complex genetics disorders: ...
A series of Lectures on Genetic Analysis, given during the 19th Course in Medical Genetics, 26th April, 2006, Bertinoro, Italy. H.Brunner: Genotypes and phenotypes; G.Stevanin: Linkage analysis; G.Romeo: From mendelian genetics to complex genetics disorders: the model of Hirschprung disease.
Sliding between adjacent microtubules within the axonema gives rise to the motility of cilia and ļ¬‚agella. The driving force is produced by dynein complexes which are mainly composed of the axonemal dynein heavy chains. We used cells of human respiratory epithelium after in vitro ciliogenesis to cl ...
We report linkage of a family affected with autosomal dominant hereditary spastic paraparesis (HSP) and/or cognitive impairment to the HSP locus on chromosome 2p. To date all families linked to this locus have been affected with ā€˜pureā€™ HSP. The speciļ¬c pattern of cognitive impairment in this f ...
A previously unrecognised X-chromosomal mental retardation syndrome is described. Clinical hallmarks are mental retardation, epileptic seizures, hypogonadism, and -genitalism, microcephaly and obesity. Life expectancy of patients is less than two years. Based on the major clinical symptoms this cond ...
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