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Coeliac disease has a multifactorial background, but there is no doubt that the genetic component give the largest contribution to the disease. Incidence within families is ten times the incidence among unrelated individuals. The concordance between monozygotic twins is above 80%, as compared to t ...
Neural crest cells (NCC) form in the human embryo during the third to fifth weeks of pregnancy by migrating away from the neuroepithelium, itself derived from the ectoderm. NCC derivatives include the neurons and support cells of the entire peripheral nervous system (sensory and autonomic), adrenerg ...
Neurulation is a key event in central nervous system development, in which bending and subsequent fusion of the edges of the neural plate culminates in the formation of the neural tube, the precursor of the brain and spinal cord [1]. Failure of neural tube closure results in neural tube defects (NT ...
The autonomic or visceral nervous system (VNS) is a set of reflex circuits, passing through the hindbrain and spinal cord, that maintains bodily homeostasis, through the regulation of three cardinal functions: respiratory, cardiovascular and digestive. It has emerged over the past ten years that, qu ...
Diabetes mellitus is a metabolic derangement in which carbohydrate utilization is reduced by decreased insulin or resistance to insulin. Type 1 diabetes is juvenile onset (usually less than age 20 years), insulin dependent and associated with normal or wasted body habitus and low to absent plasma in ...
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