Parametric and Non-Parametric Linkage Analysis

Submitted: Saturday 18th of September 2010 03:43:59 PM
Submitted by: Mohammed-E Twfieg
Language: English
Educational levels: qc1, qc2

Abstract

This Learning Package contains two learning packages, one in Parametric and the other in Non-Parametric Linkage Analysis. The material in the learning packages was part of the MSc in Genetic Epidemiology at the University of Sheffield.

Resources

This Learning Package contains lectures on Parametric Linkage analysis, which were delivered as part of the MSc in Genetic Epidemiology at the University of Sheffield.
This Learning Package contains lectures in Non - parametric Linkage analysis, which were taught as part of the MSc in Genetic Epidemiology at the University of Sheffield.

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Keywords

additive, admixture, admixture test, adoption, affected, affected sib-pair, affected sibpair, algorithm, allele, allele frequency, allelic heterogeneity, ascertainment, association, association studies, autosome, autozygosity, bacterial artificial chromosome, base, base pair, bioinformatics, BRCA, carrier, cell, centimorgan, centromere, chiasma, chromatid, chromosome, conditional probability, consanguineous marriage, consanguinity, correlation, coupling, deoxyribonucleic acid, diploid, discordant, dominance, dominant, environmental factor, epistasis, ER, false positive result, familial, fastlink, fixed, founder, founder effect, frequency, gamete, gene, gene flow, genehunter, genetic heterogeneity, genetic map, genetic map distance, genetic mapping, genetic marker, genetic variation, genetics, genome, genome scan, genotype, genotypic relative risk, genotyping, haldane map function, haploid, hereditary, hereditary non-polyposis colorectal cancer, heritability, heterogeneity, heterogeneous, homogeneity, hotspot, ibs, identity by descent, inbreeding, incidence, incomplete penetrance, informative, inheritance vector, interference, linkage, linkage analysis, location score, locus, locus heterogeneity, lod score, loss of heterozygosity, mapping function, marker, maternal, maximum lod score, mean test, meiosis, mendelian inheritance, merlin, mode of inheritance, monogenic, multilocus, multipoint, mutation, parametric linkage analysis, parental, pedigree, penetrance, phase known, phase unknown, phenotype, physical distance, polymorphism, population, population isolate, posterior probability, power, predisposing mutation, predisposition, prevalence, prior probability, probability, qualitative, quantitative, quantitative trait, recessive, recessive gene, recombinant, recombination, recombination fraction, regression, relative risk, replication, repulsion, segregation, segregation analysis, sensitivity, sib, sib pair, single nucleotide polymorphism, sister chromatids, sporadic, syndrome, telomere, threshold, trait, twin studies, unaffected, variance, variation

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