Chromatin Architecture Of The Human Genome

Submitted: Wednesday 4th of August 2010 05:18:47 PM
Submitted by: egf
Language: English
Educational levels: qc1, qc2, qc3

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Abstract

This resource contains materials from advanced courses of cytogenetics and it is especially focused on. basic principle on nuclei architecture.

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Basic principles of the space-time organization and arrangements of chromatin in interphase nuclei have become apparent, including the distinctly different, spatial arrangement of early versus mid-to-late replicating chromatin, the non-random, radial arrangement of gene dense and gene poor chromatin ...
Increasing attention has been paid in the last years to the functional relevance of higher order chromatin arrangement in the nucleus as an epigenetic mechanism of gene regulation beyond regulatory sequences and local chromatin configuration. This concerns e.g. the positioning of a gene locus with ...
Increasing attention has been paid in the last years to the functional relevance of higher order chromatin arrangement in the nucleus as an epigenetic mechanism of gene regulation beyond regulatory sequences and local chromatin configuration. This concerns e.g. the positioning of a gene locus with ...
Basic principles of the space-time organization and arrangements of chromatin in interphase nuclei have become apparent, including the distinctly different, spatial arrangement of early versus mid-to-late replicating chromatin, the non-random, radial arrangement of gene dense and gene poor chromatin ...
Metaphase chromosomes show a segmented linear organization with clusters of low and high gene density, some of them representing regions of ubiquitously increased gene expression (RIDGES), of different replication timing, DNA composition and compactness. These features partially coexist on the linea ...
Metaphase chromosomes show a segmented linear organization with clusters of low and high gene density, some of them representing regions of ubiquitously increased gene expression (RIDGES), of different replication timing, DNA composition and compactness. These features partially coexist on the linea ...
About 5% of the human genome is composed of segmental duplications (Bailey et al. 2005). A growing list of diseases can be directly or indirectly connected to segmental duplications. Sequence homology between duplicated DNA segments, in fact, provides a chance for misalignment during meiosis, leadin ...
About 5% of the human genome is composed of segmental duplications (Bailey et al. 2005). A growing list of diseases can be directly or indirectly connected to segmental duplications. Sequence homology between duplicated DNA segments, in fact, provides a chance for misalignment during meiosis, leadin ...
Human cells package their DNA into chromatin, a nucleoprotein complex. In chromatin the DNA is wrapped 1.75 times around a nucleosome, consisting of an octamer of histone proteins. Under physiological salt conditions nucleosome arrays adopt the conformation of a 30nm fibre. Cellular processes such a ...
Human cells package their DNA into chromatin, a nucleoprotein complex. In chromatin the DNA is wrapped 1.75 times around a nucleosome, consisting of an octamer of histone proteins. Under physiological salt conditions nucleosome arrays adopt the conformation of a 30nm fibre. Cellular processes such a ...
Human cells package their DNA into chromatin, a nucleoprotein complex. In chromatin the DNA is wrapped 1.75 times around a nucleosome, consisting of an octamer of histone proteins. Under physiological salt conditions nucleosome arrays adopt the conformation of a 30nm fibre. Cellular processes such a ...

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Keywords

acetylation, affected, alpha, Analysis of the entire coding region: Sequence analysis, association, autosomal, bacterial artificial chromosome, band, banding, base pair, beta, biotechnology, blastocyst, cell, cell cycle, cell line, centromere, chromatin, chromatin fiber, chromosomal analysis, chromosome, chromosome abnormality, cis configuration, clone, comparative genomics, correlation, Cytogenetic Abnormality, cytogenetics, de novo, deletion, deoxyribonucleic acid, diploid, discordant, DNA methylation, dna microarray, dna probe, dna repair, dna replication, domain, duplication, embryo, epigenetics, euchromatin, exon, expansion, expectation maximization algorithm, expression, fibroblast, FISH-interphase, fixed, fluorescent in situ hybridization, g band, gene, gene expression, gene transcription, genetics, genome, germline, heredity, heterochromatin, histone, homogeneity, homologous, hybridization, in situ hybridization, in vitro fertilisation, inherited, insertion, interphase, karyotype, kilobase, locus, marker, metaphase, methylation, microarray, mitosis, monozygotic twins, Multicolor FISH, mutant, mutation, natural selection, nuclear envelope, nuclear pores, nucleosome, nucleus, orthologous, paint, phase, plasma cell, population, predisposition, probe, processing, protein, quantitative, rearrangement, recombination, replication, retina, ribonucleic acid, roentgen equivalent for man, satellite, segmental duplication, sensitivity, sequence, short interspersed nuclear elements, single nucleotide polymorphism, somatic mosaicism, specie, sperm, splicing, stem cell, syndrome, transcription, transformation, variation, zygote

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