Cancer Cytogenetics

Submitted: Saturday 31st of July 2010 06:08:47 PM
Submitted by: egf
Language: English
Educational levels: qc1, qc2, qc3

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Abstract

This resource contains materials from advanced courses of cytogenetics and it is especially focused on Cancer Cytogenetics.

Resources

Immense amounts of data on neoplasia-associated chromosomal aberrations have been collected during the last three decades. At present chromosome abnormalities identified by various banding techniques have been described in more than 48 000 human neoplasms. An increasing number of these aberrations h ...
A lecture about FISH in hematological malignancies: the Workshop by C.T. Strolazzi in 2007, 9th course in molecular cytogenetics and DNA microarray
Fluorescence In Situ Hybridizaion (FISH) is a powerful tool to identify chromosomal aberrations for diagnosis as well as for prognostic stratification of leukemias and lymphomas. Both interphase and metaphase FISH may be applied to investigate numerical and structural chromosome changes. Interphase ...
Fluorescence In Situ Hybridizaion (FISH) is a powerful tool to identify chromosomal aberrations for diagnosis as well as for prognostic stratification of leukemias and lymphomas. Both interphase and metaphase FISH may be applied to investigate numerical and structural chromosome changes. Interphase ...
Cancer is a multistep process in which more than one specific gene (among proto-oncogenes, tumor-suppressor genes and mutator genes) undergoes mutational events that could alter the normal expression pattern. It is well known that regulatory or structural alterations of cellular oncogenes have been ...
A lecture on FISH technology in leukemia.
A lecture about FISH in leukemias by C. Mecucci
Many thousands of single nucleotide polymorphisms SNPs have been identified in the human genome. These normal variations have been particularly useful in the study of loss of heterozygosity (LOH) in cancer, in linkage studies of patterns of familial inheritance and in the search for low penetrance g ...
Many single nucleotide polymorphisms (SNPs) have been identified in the human genome. These normal variations have been particularly useful in the study of loss of heterozygosity (LOH) in cancer, in linkage studies of patterns of familial inheritance and in the search for low penetrance genes associ ...

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Keywords

abnormal, affected, alternative splicing, Analysis of the entire coding region: Mutation scanning, Analysis of the entire coding region: Sequence analysis, antigen, antigen binding fragment, Array genomic hybridization, bacterial artificial chromosome, band, banding, base, base pair, break-point cluster, candidate gene, cell, cell line, centromere, chromosome, chromosome walking, clone, Complementary DNA, connective tissue, cosmid, Cytogenetic Abnormality, cytogenetics, deletion, deoxyribonucleic acid, differentiate, discordant, dna microarray, dna probe, domain, duplication, enhancer, environmental factor, exon, expressed gene, expression, FISH-metaphase, fluorescent in situ hybridization, gene, gene amplification, gene chip, gene cloning, gene expression, genetics, genome, heterochromatin, high throughput, histone, homeobox, homogeneity, homogeneously staining region, hybridization, immunohistochemistry, in vitro, index case, insertion, interphase, interstitial deletion, intron, inv, inversion, isolated, karyotype, kilobase, locus, loss of heterozygosity, marker, messenger rna, metaphase, microarray, microrna, monosomy, Multicolor FISH, multivariate, oligonucleotide, oncogene, parental, phenotype, plasmid, point mutation, polymerase chain reaction, population, probe, processing, promoter, protein, proto-oncogene, rearrangement, reciprocal translocation, replication, repressor, reverse transriptase pcr, ribonucleic acid, selection, sensitivity, sequence, sex-determining region of the y, signal transduction, specie, specificity, Spectral Karyotyping, subtelomeric region, syndrome, synthesis, target dna, telomere, transcript, transcription factor, translocation, trisomy, tumor suppressor gene, uninformative, untranslated region, variant, variation, vector, yeast artificial chromosome

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