2nd Course in The integration of cytogenetics, microarrays and massive sequencing in biomedical and clinical research - B

Submitted: Monday 4th of October 2010 07:16:04 AM
Submitted by: egf
Language: English
Educational levels: expert, qc3

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Abstract

Part B of the 2nd Course in The integration of cytogenetics, microarrays and massive sequencing in biomedical and clinical research

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Microarray technology enables the concurrent collection and mining of data from thousands of genes or chromosomal locations. The first type of array that was introduced measures the expression of genes; called expression array (Brown, Botstein, 1999). This technology now has matured for over 10 year ...
Array Comparative Genomic Hybridization (array CGH) is the high-resolution laboratory technique of choice for the detection of chromosomal DNA copy number aberrations on a genome-wide scale (Costa et al., 2008). To perform array CGH initially PCR amplified bacterial artificial chromosomes (BACs) or ...
The widespread use of array–comparative genomic hybridization (array-CGH) for the detection of copy number variants (CNVs) in both research and clinical laboratories has created a renaissance in the field of molecular cytogenetics, revealing that the human genome contains both a wealth of structur ...
MicroRNAs are an emerging class of small non-coding RNAs implicated in a wide variety of biological and cellular processes. Research in this field is accelerating and the growing number of miRNAs emphasizes the need for high throughput and sensitive detection methods. We present the successful evalu ...

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